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Postdoc (f/m/x) in Köln

Arbeiten an der Uniklinik Köln heißt die Zukunft mitgestalten. Finden Sie jetzt die richtige Ausbildung und werden Sie ein Teil von uns.


» Your tasks
  • Carrying out animal experiments including corneal transplantation in a mouse model, immunological assays (MLR, DC-T cell co-culture etc.), in vivo microscopy, siRNA, and flow cytometry
  • Designing and performing experiments using cell/molecular biology/immunological techniques (proliferation, migration, tube formation, adhesion, qPCR, ELISA, Western Blot), immunohistochemistry, imaging analysis (immunofluorescence, confocal, optical coherence tomography (OCT) and/or microscopic optical coherence tomography (mOCT))
  • Presentation and publication of the findings
» Your Profile
  • Hold a PhD in Biology, Biochemistry, Molecular Medicine or comparable
  • Have a strong interest in lymphangiogenesis or angiogenesis, stem cell research and/or immunology
  • Have profound knowledge of techniques used in molecular biology, cell biology and immunology (strongly preferred)
  • Be willing to carry out animal experiments
  • Be strongly motivated to do independent experimental work
  • Good knowledge of English
» Our Offer
  • Excellent laboratory facilities, excellent opportunities for international scientific networking on the Cologne Life Sciences campus, and specific support for female scientists
» Your future in detail

Functional relevance and molecular mechanisms of tyrosinase in controlling lymphangiogenesis in different ocular diseases

This project is associated with the research group FOR 2240 "" (speaker: Univ.-Prof. Dr. med. Claus Cursiefen, FEBO, FARVO and vice-speaker: Univ.-Prof. Dr. rer. nat. Thomas Langmann) at the , University Hospital Cologne.

The cornea is one of the few tissues that is physiologically avascular. The avascularity of the cornea is a prerequisite for its transparency which is maintained by an active process involving the production of anti-(lymph)angiogenic factors to counterbalance proangiogenic factors. However, diseases of the eye, like infections or chemical burns, can destroy the balance between pro- and anti-(lymph)angiogenic factors, which leads to ingrowth of blood and lymphatic vessels. Currently, however, no treatment strategies are clinically available to specifically modulate lymphangiogenesis. Recently, tyrosinase, a key enzyme in melanogenesis, was discovered as novel regulator of the developmental and inflammation induced lymphangiogenesis. The aim of this project is to gain a better understanding of the functional relevance and the molecular mechanisms of tyrosinase in regulating (pathological) ocular lymphangiogenesis.

Applications from female candidates are expressly welcome and will be given priority in the event of equal suitability, competence and professional performance.

People with disabilities are welcome to apply and will be treated preferentially in the event of equal suitability and qualification.

The position is suitable for staffing with part-time employees.


Dr. Thomas Clahsen or Esther Engel
+49 221 478-85618

Application deadline: 12.05.2022

Postal address:

Universitätsklinikum Köln AöR
Geschäftsbereich Personal
Job-ID: 00002913
50937 Köln

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Medizin / Gesundheitswesen
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